How to Make Classic Meatloaf – The Ultimate Comfort Food 2025

Classic Meatloaf – Easy Recipes with Ground Beef for a Hearty Dinner

There’s something magical about a hearty, homemade meal that brings everyone to the table with smiles and satisfied appetites. One dish that stands the test of time, generation after generation, is the classic meatloaf. Made from humble ingredients like ground beef, onions, breadcrumbs, and a touch of seasoning, this iconic comfort food recipe is rich, savory, and incredibly easy to prepare—even on your busiest weeknight.

In this article, you’ll discover everything you need to know to make the perfect meatloaf from scratch: from the best type of ground beef to use to pro tips for keeping it moist and flavorful. We’ll also cover how to store leftovers, how to make it ahead for meal prep, and creative variations you can try to make it your own.

Whether you’re craving something nostalgic or simply need a no-fail meal for a weeknight dinner, this classic meatloaf recipe delivers every single time.


🍽️ Why We Love Classic Meatloaf

Classic meatloaf holds a nostalgic place in many hearts. It’s one of those dishes that brings back memories of family dinners, holiday gatherings, and simple pleasures. But beyond sentimentality, meatloaf is also incredibly versatile, budget-friendly, and full of rich, savory flavor.

Unlike more complicated meals that require hard-to-find ingredients or expensive cuts of meat, meatloaf makes use of pantry staples and affordable ground beef. It’s the perfect recipe to stretch your grocery budget without sacrificing taste or comfort.

Plus, it’s:

  • Freezer-friendly
  • Great for leftovers and sandwiches
  • Easily customizable (add veggies, herbs, cheeses, or even bacon!)
  • Perfect for both casual dinners and family gatherings

🛒 Ingredients for Classic Meatloaf

To make the perfect meatloaf, you’ll need the following ingredients. These are carefully balanced to ensure moistness, structure, and that traditional meatloaf taste.

Essential Ingredients

  • 2 pounds ground beef (80/20 blend is ideal)
  • 1 cup breadcrumbs (plain or seasoned)
  • 1 medium yellow onion, finely chopped
  • 2 large eggs
  • ¾ cup milk (whole or 2% recommended)
  • 2 teaspoons salt
  • ½ teaspoon black pepper
  • ½ teaspoon garlic powder
  • ½ teaspoon onion powder
  • ¼ cup ketchup (for mixing)
  • ¼–½ cup ketchup (for glaze topping)

Optional Add-ins for More Flavor

  • ½ cup grated cheddar or mozzarella cheese
  • 2 tablespoons chopped parsley
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon Dijon mustard
  • 2 tablespoons brown sugar (for a sweet glaze)

👨‍🍳 Step-by-Step Instructions

Step 1: Preheat Oven and Prepare Pan

Preheat your oven to 375°F (190°C). Line a loaf pan with parchment paper or lightly grease it with oil. You can also free-form the meatloaf on a baking sheet if you prefer a crisper exterior.

Step 2: Combine Ingredients

In a large mixing bowl, combine the ground beef, breadcrumbs, chopped onion, eggs, and milk. Add the salt, pepper, garlic powder, onion powder, and ¼ cup ketchup.

Mix with your hands or a wooden spoon just until combined. Avoid overmixing, as that can make the meatloaf dense.

Step 3: Form the Loaf

Shape the mixture into a loaf and place it in the prepared pan. Smooth the top and edges.

Step 4: Glaze and Bake

Spread a generous layer of ketchup (or your preferred glaze) over the top. This not only adds flavor but also helps seal in moisture.

Place in the oven and bake for 55–60 minutes, or until a meat thermometer inserted in the center reads 160°F (71°C).

Step 5: Let It Rest

Remove from the oven and allow the meatloaf to rest for at least 10 minutes before slicing. This helps the juices redistribute evenly for moist, flavorful slices.


💡 Secrets to a Perfectly Moist Meatloaf

  1. Use milk and eggs generously: They create a rich binder and keep the loaf tender.
  2. Choose the right beef: An 80/20 fat ratio is ideal—leaner meat can result in dryness.
  3. Don’t overmix: Stir until combined, then stop. Overmixing compacts the loaf.
  4. Resting time is key: This lets the juices settle and prevents a crumbly texture.
  5. Glaze it well: A ketchup or BBQ glaze locks in moisture and adds sweetness and tang.

🧂 Flavor Variations to Try

Want to give your meatloaf a fresh twist? Try one of these tasty upgrades:

  • Italian Meatloaf: Add oregano, basil, and mozzarella cheese; top with marinara.
  • Tex-Mex Meatloaf: Add taco seasoning, corn, and shredded pepper jack.
  • BBQ Bacon Meatloaf: Mix in crumbled cooked bacon and glaze with BBQ sauce.
  • Mushroom Swiss Meatloaf: Stir in sautéed mushrooms and Swiss cheese.
  • Turkey Meatloaf: Use ground turkey and add extra milk or a tablespoon of olive oil for moisture.

⏲️ How to Make Classic Meatloaf Ahead of Time

Meal prepping meatloaf is a huge time-saver.

Option 1: Refrigerate Before Baking

Assemble the loaf, wrap tightly in foil or plastic wrap, and refrigerate for up to 24 hours before baking.

Option 2: Freeze for Later

Wrap the uncooked loaf in plastic wrap and foil. Label it with the date and freeze for up to 3 months. To bake, thaw overnight in the fridge and proceed as usual.


🧊 How to Store and Reheat Leftovers

Refrigerating Leftovers

Wrap leftovers in foil or store in an airtight container. It will stay fresh in the fridge for up to 4 days.

Freezing Leftovers

Slice meatloaf and wrap individual slices in wax paper. Store in a freezer-safe zip-top bag for up to 3 months.

Reheating Tips

  • Microwave: Cover with a damp paper towel to avoid drying out.
  • Oven: Wrap in foil and heat at 300°F for 10–15 minutes.
  • Air Fryer: Reheat for a few minutes at 350°F to regain crispiness.

🥗 What to Serve with Meatloaf

Pair your meatloaf with one or more of these classic sides:

  • Creamy mashed potatoes
  • Green beans almondine
  • Macaroni and cheese
  • Roasted carrots
  • Buttered corn
  • Garlic bread or dinner rolls
  • A crisp garden salad

🧾 Classic Meatloaf Recipe Card

Prep Time: 15 minutes
Cook Time: 60 minutes
Rest Time: 10 minutes
Total Time: 1 hour 25 minutes
Servings: 6
Course: Main Course
Cuisine: American

📝 Ingredients

  • 2 lbs ground beef (80/20)
  • 1 cup breadcrumbs
  • 1 medium onion, chopped
  • 2 large eggs
  • ¾ cup milk
  • 2 tsp salt
  • ½ tsp black pepper
  • ½ tsp garlic powder
  • ½ tsp onion powder
  • ¼ cup ketchup (in mixture)
  • ¼–½ cup ketchup (for glaze)

🧑‍🍳 Instructions

  1. Preheat oven to 375°F (190°C).
  2. Mix all ingredients in a large bowl, saving some ketchup for topping.
  3. Shape into a loaf and place in a pan or on a lined baking sheet.
  4. Spread remaining ketchup on top.
  5. Bake 55–60 minutes or until internal temperature reaches 160°F.
  6. Rest for 10 minutes. Slice and serve.

❓ FAQs About Meatloaf

Q: How can I tell when meatloaf is done?

Use a food thermometer. The center should reach 160°F (71°C).

Q: Can I make meatloaf gluten-free?

Yes! Use gluten-free breadcrumbs or rolled oats instead.

Q: What’s the best meat for meatloaf?

Ground beef with 20% fat is ideal for moisture and flavor.

Q: Can I make it in an air fryer?

Absolutely! Form smaller loaves and air fry at 350°F for 20–25 minutes.


🍲 More Ground Beef Dinner Ideas

Love ground beef recipes? Try these next!

  • Cheesy One-Pot Macaroni Cheeseburger
  • Hobo Casserole – Hearty Family Dinner
  • Korean Ground Beef Bowl
  • Beef and Cheese Chimichangas

❤️ Final Thoughts

Classic meatloaf is more than just a dish—it’s a tradition. With simple ingredients, a straightforward process, and a flavor profile everyone loves, it’s no wonder this recipe remains a staple in kitchens across the country.

Whether you’re cooking for your kids, hosting a family dinner, or just treating yourself to something warm and satisfying, this meatloaf delivers. And once you master it, you’ll find it endlessly adaptable to your tastes and lifestyle.

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